Lv1
28 积分 2024-11-28 加入
Discovery of a Proteolysis-Targeting Chimera Degrader of JAK2 as a Potential Therapeutic Agent for JAK2-Mediated Myeloproliferative Neoplasms
1个月前
已完结
N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms
1个月前
已完结
JAK inhibitor selectivity: new opportunities, better drugs?
4个月前
已完结
Pharmacological Modulation of the Crosstalk between Aberrant Janus Kinase Signaling and Epigenetic Modifiers of the Histone Deacetylase Family to Treat Cancer
6个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐related Kinase 7
10个月前
已完结
Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders
10个月前
已完结
Combination of ligand‑based and structure‑based virtual screening for the discovery of novel Janus kinase 2 inhibitors against philadelphia-negative myeloproliferative neoplasms
11个月前
已完结