Lv1
20 积分 2024-10-18 加入
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
5个月前
已完结
Expanding the binding space of argonaute-2: incorporation of either E or Z isomers of 6′-vinylphosphonate at the 5′ end of the antisense strand improves RNAi activity
5个月前
已完结
Obesity reduces the urate-lowering efficacy among patients with primary gout: a prospective cohort study
6个月前
已完结
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
7个月前
已完结
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
7个月前
已完结
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer
7个月前
已完结
Genetically engineering cells to produce therapeutically boosted extracellular vesicles for cardiovascular calcification
7个月前
已完结
RNA chemistry and therapeutics
7个月前
已完结
Using RNA therapeutics to promote healthy aging
7个月前
已完结
Polyethylene Glycol-Mediated Fusion of Extracellular Vesicles with Cationic Liposomes for the Design of Hybrid Delivery Systems
7个月前
已完结