Lv4
710 积分 2021-07-06 加入
Discovery of Highly Selective and Potent Macrocyclic JAK2 Inhibitors for the Treatment of MPNs
2天前
已完结
Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain expos
2天前
已完结
Structure-Based Design of a Novel Covalent 4-(1-Methylindol-3-yl)pyrimidin-2-amine Series Targeting FGFR2 Resistance Mutations
3个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
4个月前
已完结
Structure-Based Design of 4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine Derivatives as the First Covalent FGFR3 Selective Inhibitors
5个月前
已完结
Pemigatinib for Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement
5个月前
已完结
Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study
5个月前
已完结
Oral Infigratinib Therapy in Children with Achondroplasia
5个月前
已完结
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity acrossFGFR2Alterations and Resistance Mutations
6个月前
已完结
Structural and Functional Diversity in the FGf Receptor Multigene Family
6个月前
已完结
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