Lv4
630 积分 2024-04-07 加入
Charged molecular glue discovery enabled by targeted degron display
12天前
已完结
Harnessing FBXO31 with Terminal Amide-Functionalized Molecules for Targeted Protein Degradation
16天前
已完结
Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence
19天前
已完结
Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer
19天前
已完结
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression
19天前
已完结
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras
29天前
已完结
Turning KEAP1 against NRF2
1个月前
已完结
Turning KEAP1 against NRF2
1个月前
已完结
Modulation of the 14-3-3σ/C-RAF "Auto"inhibited Complex by Molecular Glues
2个月前
已关闭
Identification of an allosteric site on the E3 ligase adapter cereblon
3个月前
已完结
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