Lv4
600 积分 2024-04-07 加入
Brønsted-basic small molecules activate GTP hydrolysis in KRAS-Q61 mutants
10小时前
待确认
Bronsted-basicsmallmoleculesactivate GTPhydrolysisinKRAS-06lmutants
10小时前
已关闭
A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition
28天前
已完结
Generation of membrane-permeable cyclic peptides inhibiting protein-protein interaction
1个月前
已完结
Discovery of the First Potent, Selective, and In Vivo Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of TRIM37-Amplified Breast Cancer
1个月前
已完结
Molecular Glue Degraders of HuR Suppress BRAF-Mutant Colorectal Cancer
1个月前
已完结
Charged molecular glue discovery enabled by targeted degron display
3个月前
已完结
Harnessing FBXO31 with Terminal Amide-Functionalized Molecules for Targeted Protein Degradation
4个月前
已完结
Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence
4个月前
已完结
Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer
4个月前
已完结
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