Lv13
64 积分 2025-03-03 加入
Disrupted ubiquitin proteasome system underlying tau accumulation in Alzheimer’s disease
1年前
已完结
Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP
1年前
已完结
Phase 1 study of HP518, a PROTAC AR degrader in patients with mCRPC: results on safety, pharmacokinetics, and anti-tumor activity
1年前
已完结
Development of targeted protein degradation therapeutics
1年前
已完结
How do protein aggregates escape quality control in neurodegeneration?
1年前
已完结
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson’s disease
1年前
已完结
Engineered commensals for targeted nose-to-brain drug delivery
1年前
已完结
A heparanase-specific LYTAC degrader reinforces natural killer cell cytotoxicity within the tumor microenvironment
1年前
已完结
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