Lv4
588 积分 2023-10-23 加入
Correlation of the in vitro biotransformation of H3B-6527 in dog and human hepatocytes with the in vivo metabolic profile of 14C-H3B-6527 in a dog mass balance study
1天前
已完结
Correlation of the in vitro biotransformation of H3B-6527 in dog and human hepatocytes with the in vivo metabolic profile of 14C-H3B-6527 in a dog mass balance study
1天前
已完结
Identification and characterization of in silico, in vivo, in vitro, and reactive metabolites of infigratinib using LC-ITMS: bioactivation pathway elucidation and in silico toxicity studies of its metabolites
1天前
已完结
Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications
1天前
已完结
Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity
1天前
已完结
3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation
1天前
已完结
Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma
1天前
已完结
Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers
1天前
已完结
Insight into the design of FGFR4 selective inhibitors in cancer therapy: Prospects and challenges
1天前
已完结
Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability
1天前
待确认
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