Lv21
120 积分 2024-07-11 加入
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice
2小时前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
3小时前
已完结
Identification of Novel Series of Potent and Selective Relaxin Family Peptide Receptor 1 (RXFP1) Agonists
1个月前
已完结
LSD1 inhibitors for anticancer therapy: an updated patent review (2022–2025)
2个月前
已完结
From Chiral Separation to Asymmetric Synthesis: Route Scouting and Early Process Development of a Chiral Tetrahydrofuran–Pyrazolamine Intermediate of CDK2 Inhibitor RLY-2139
2个月前
已完结
Process Development and Scale-Up of RLY-2139: A Selective CDK2 Inhibitor Targeting ER+/HER2– Breast Cancer
2个月前
已完结
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
2个月前
已完结
Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution
3个月前
已完结
Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis
3个月前
已完结
Peptide Bond-Forming Reaction via Amino Acid Silyl Esters: New Catalytic Reactivity of an Aminosilane
3个月前
已完结
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