Lv11
32 积分 2026-04-14 加入
Structure–activity landscape of Nurr1 (NR4A2) modulators: medicinal chemistry strategies for neurodegenerative disease intervention
42分钟前
待确认
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism
4小时前
已完结
In silico identification of NPACT-derived PAK1 inhibitors using machine learning, molecular docking, and dynamic simulation approaches
14天前
已完结
In silico identification of NPACT-derived PAK1 inhibitors using machine learning, molecular docking, and dynamic simulation approaches
16天前
已完结
Conformation-driven design, synthesis and biological evaluation of novel PAK1 inhibitors that downregulate PD-L1 for triple-negative breast cancer therapy
16天前
已完结
Identification of Balanol As a Potential Inhibitor of PAK1 That Induces Apoptosis and Cytoprotective Autophagy in Colorectal Cancer Cells
16天前
已完结
Design, Synthesis, and Biological Evaluation of Novel PAK1/HDAC10 Dual Inhibitors That Activate Antitumor Immunity for Triple-Negative Breast Cancer Treatment
29天前
已完结
Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2
1个月前
已完结
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitors
1个月前
已完结
Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6
1个月前
已完结
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