Lv1
30 积分 2025-07-04 加入
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
7个月前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
7个月前
已完结
GDC-0077 is a selective PI3Kalpha inhibitor that demonstrates robust efficacy in PIK3CA mutant breast cancer models as a single agent and in combination with standard of care therapies
7个月前
已关闭
Discovery of First-in-Class TAK1-MKK3 Protein-Protein Interaction (PPI) Inhibitor ( R)-STU104 for the Treatment of Ulcerative Colitis through Modulating TNF-α Production
10个月前
已完结
The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations
10个月前
已完结
Exploring a kinase inhibitor targeting PI3KCA mutant cancer cells
10个月前
已完结
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