Lv4
570 积分 2023-04-17 加入
Discovery of an Indole-Based p53-Y220C Reactivator with In Vivo Antitumor Activity via Structure-Guided Design
18天前
已完结
New indolin-2-ones, possessing sunitinib scaffold as HDAC inhibitors and anti-cancer agents with potential VEGFR inhibition activity; design, synthesis and biological evaluation
21天前
已完结
Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development
1个月前
已完结
Small molecules that targeting p53 Y220C protein: mechanisms, structures, and clinical advances in anti-tumor therapy
1个月前
已完结
RIPTACs: A groundbreaking approach to drug discovery
1个月前
已完结
Generating Surprisingly Powerful Pharmacology from Chemically Induced Protein Interactions
1个月前
已完结
Proteomics-Driven Strategies for Proximity-Inducing Drug Discovery
1个月前
已完结
Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
1个月前
已完结
Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
1个月前
已完结
Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma
2个月前
已完结
皖公网安备34019202002308
