Lv41
710 积分 2023-09-25 加入
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
1个月前
已完结
Discovery of JAB-3312, a Potent SHP2 Allosteric Inhibitor for Cancer Treatment
2个月前
已完结
Nickel-Catalyzed Intramolecular Hydroalkenylation of Imines
3个月前
已完结
Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates
3个月前
已完结
Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability
3个月前
已完结
Sulfilimines from a Medicinal Chemist’s Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
3个月前
已完结
Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation
3个月前
已完结
Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair
4个月前
已完结
Closing the Design–Make–Test–Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability
4个月前
已完结
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