Lv41
660 积分 2023-09-25 加入
Nickel-Catalyzed Intramolecular Hydroalkenylation of Imines
3小时前
待确认
Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates
1天前
已完结
Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability
13天前
已完结
Sulfilimines from a Medicinal Chemist’s Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
16天前
已完结
Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation
16天前
已完结
Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair
1个月前
已完结
Closing the Design–Make–Test–Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability
1个月前
已完结
Development of a Buchwald–Hartwig Amination for an Accelerated Library Synthesis of Cereblon Binders
2个月前
已完结
Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization
2个月前
已完结
Structural insight into selectivity of amylin and calcitonin receptor agonists
2个月前
已完结
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