Lv41
800 积分 2023-09-25 加入
Antibody-Mediated Delivery of BRM/BRG1 Protein Degraders Affords Strong Antitumor Efficacy in Multiple BRM-Dependent Non-Small Cell Lung Cancer Xenograft Models
8小时前
已完结
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
11小时前
已完结
Discovery and Preclinical Characterization of I-0436650, a Selective SHP2 Allosteric Inhibitor for RAS-Driven Cancers
12小时前
已完结
Discovery andCharacterization of RP04340 : A Highly Potent and OrallyActive Pan-KRAS PROTAC Degrader
12小时前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
1个月前
已完结
Discovery of AZD9750, an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
1个月前
已完结
Linker-Driven Sampling of PROTAC-Induced Ternary Complexes
1个月前
已完结
Catalytic Reductive Amination and Tandem Amination–Alkylation of Esters Enabled by a Cationic Iridium Complex
1个月前
已完结
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
1个月前
已完结
Universal Reagent for Mild and Stereospecific Nucleophilic Substitution of Alcohols with Amines
4个月前
已完结
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