Lv5
969 积分 2021-03-29 加入
E3 ligase ligand chemistries: from building blocks to protein degraders
6天前
已完结
Discovery of an Ultrasound-Responsive Arylurea-Dihydrotetrazine Architecture for Ultrasound-Programmed Bioorthogonal Chemistry
7天前
已完结
Precursors of Carboximidates Deriving from Thioamide-Trimethyl-Lock System: A General Method for Designing Stable Cascade Acid-Sensitive Prodrugs
7天前
已完结
Development of Cyclooctyne-Nitrone Based Click Release Chemistry for Bioorthogonal Prodrug Activation both In Vitro and In Vivo
7天前
已完结
Photodynamic Hijacking of APE1 Converts Tumor Defenses into Therapeutic Vulnerabilities via a Bidirectionally Gated Prodrug
8天前
已完结
A chimeric peptide promotes immune surveillance of senescent cells in injury, fibrosis, tumorigenesis and aging
8天前
已完结
Blood-Brain Barrier-Permeable Macrocyclic Chimeras (BmTACs) for Targeted Protein Degradation in the Aging Brain
20天前
已完结
Chemical Genetic Control of Protein Levels: Selective in Vivo Targeted Degradation
21天前
已完结
A Click-Triggered Bioorthogonal Strategy for Dual Activation of Covalent Warheads and Reporter Payloads
22天前
已完结
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
23天前
已完结