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Intraperitoneal administration of carcinoembryonic antigen-directed chimeric antigen receptor T cells is a robust delivery route for effective treatment of peritoneal carcinomatosis from colorectal cancer in pre-clinical study
1个月前
已完结
Hypoxia-Responsive CAR-T Cells Exhibit Reduced Exhaustion and Enhanced Efficacy in Solid Tumors
1个月前
已完结
Hypoxia-responsive CEA-targeted CAR T cells in CEA-positive solid tumors through intraperitoneal or intravenous infusion: a phase 1 trial
1个月前
已完结
Preclinical development and a phase I trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer
5个月前
已完结
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function
8个月前
已关闭
Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity
8个月前
已完结
Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells
8个月前
已完结
CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors
9个月前
已完结
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
9个月前
已完结