Lv2
160 积分 2022-12-05 加入
Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML
6天前
已完结
Targeting the H/KRAS α4-β6-α5 Allosteric Lobe with Macrocyclic Peptides
7天前
已完结
Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry
11天前
已完结
Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation
12天前
已完结
Identification of an Orally Bioavailable Quinoline-Based Small-Molecule Tumor Necrosis Factor α (TNF-α) Inhibitor Featuring a Spirocyclic Scaffold
19天前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
21天前
已完结
Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models
26天前
已完结
Discovery of YYSW001: A Highly Selective, Orally Bioavailable JAK1 Inhibitor Achieving Efficacy under a Moderate-Inhibition Strategy with Improved Preclinical Tolerability
27天前
已完结
Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING Pathway
28天前
已完结
Reshaping Pfizer’s drug discovery priorities
30天前
已完结
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