Lv4
619 积分 2025-08-20 加入
Design and Synthesis of KRAS G12C Inhibitors for Antitumor Evaluation Harboring Combination Therapy with Nrf2, PARP-7, and Pan-USP Inhibitors to Alleviate Drug Resistance Synergistically
8天前
已完结
Discovery of highly potent PARP7 inhibitors for cancer immunotherapy
8天前
已完结
新型PARP7抑制剂的合成及抗肿瘤活性
8天前
已完结
Acrylamide Bioisosterism: Alkenyl Aromatic Heterocycles as Reactivity-Tunable Warheads for Covalent BTK Inhibitors
10天前
已完结
A Bis‐Boron Amino Acid for Positron Emission Tomography and Boron Neutron Capture Therapy
10天前
已完结
Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers
1个月前
已完结
Maximum Tolerated Dose (MTD) Studies in Drug Toxicology Assessments
4个月前
已完结
Design and synthesis of boron-containing diphenylpyrimidines as potent BTK and JAK3 dual inhibitors
4个月前
已完结
HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
4个月前
已完结
Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy
6个月前
已完结
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