Lv51
830 积分 2023-10-31 加入
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
1小时前
待确认
Integrating chemical priors and physical laws to mitigate hallucinations in structure-based drug design
1个月前
已完结
Electron-density-informed effective and reliable de novo molecular design and optimization with ED2Mol
1个月前
已完结
Discovery of a Novel Tripeptide Linker that Broadens the Therapeutic Window of Auristatin-Based Antibody–Drug Conjugates by Reducing Bone Marrow Toxicity
2个月前
已完结
Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases
2个月前
已完结
A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death
2个月前
已完结
Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation
4个月前
已完结
Coarse-Grained Simulation of mRNA-Loaded Lipid Nanoparticle Self-Assembly
5个月前
已完结
Role of Ionizable Lipids in SARS-CoV-2 Vaccines As Revealed by Molecular Dynamics Simulations: From Membrane Structure to Interaction with mRNA Fragments
5个月前
已完结
SMILES-BERT
5个月前
已完结