Lv5
1010 积分 2025-04-24 加入
Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2)
21天前
已完结
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3
28天前
已完结
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3
28天前
已完结
Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1
28天前
已完结
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL)
28天前
已完结
Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations
1个月前
已完结
Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
1个月前
已完结
Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers
1个月前
已完结
Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5
1个月前
已完结
A Novel Therapeutic Anti-ErbB3, ISU104 Exhibits Potent Antitumorigenic Activity by Inhibiting Ligand Binding and ErbB3 Heterodimerization
1个月前
已完结
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