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42 积分 2024-07-18 加入
KRAS/ERK2-driven stabilization of AARS1 reprograms tumor metabolism and confers Sorafenib resistance in lung adenocarcinoma
23天前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
3个月前
已完结
TRIM7 Inhibits Rabies Virus Replication by Promoting K48-Linked Ubiquitination and Degradation of RABV-M
4个月前
已完结
The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4
5个月前
已完结
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins
6个月前
已完结
Discovery of CFT8634, a Potent, Selective, and Orally Bioavailable Heterobifunctional Degrader of BRD9
6个月前
已完结
The E3 ligase tripartite motif 7 drives the progression of non-alcoholic fatty liver disease by targeting DUSP10 degradation in male mice
6个月前
已完结
Single‐step conversion of aliphatic, aromatic and heteroaromatic primary amines into piperazine‐2,6‐diones
6个月前
已完结
Two-State Reactivity in Iron-Catalyzed Alkene Isomerization Confers σ-Base Resistance
9个月前
已完结
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
11个月前
已完结
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