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196 积分 2025-02-28 加入
Multi-target neuroprotection of Atractylodes macrocephala ethyl acetate extract against Alzheimer's disease: from bioactivity-guided screening to mechanistic validation
1个月前
已完结
Structural modification of atractylenolides: synthesis and evaluation of derivatives with potent anti-Aβ aggregation and neuroprotective activities against Alzheimer's disease
1个月前
已完结
Small molecule compounds targeting G9a/GLP: Recent advances and perspectives
2个月前
已完结
G9a/GLP Modulators: Inhibitors to Degraders
2个月前
已完结
浅谈中国公司智能手表专利及产品布局
3个月前
已完结
Upregulation of ISG15 induced by MAPT/tau accumulation represses autophagic flux by inhibiting HDAC6 activity: a vicious cycle in alzheimer disease
6个月前
已完结
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization
7个月前
已完结
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
7个月前
已完结
Discovery of Atractylenolide Derivatives as Novel LSD1 Inhibitors for the Treatment of Alzheimer’s Disease
7个月前
已完结
Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in Alzheimer's disease
7个月前
已完结
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