Lv31
212 积分 2025-02-28 加入
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization
1小时前
求助中
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
5小时前
已完结
Discovery of Atractylenolide Derivatives as Novel LSD1 Inhibitors for the Treatment of Alzheimer’s Disease
16天前
已完结
Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in Alzheimer's disease
19天前
已完结
Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in Alzheimer's disease
1个月前
已完结
[1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors
1个月前
已完结
Click N-benzyl iminodiacetic acid: Novel silica-based tridentate zwitterionic stationary phase for hydrophilic interaction liquid chromatography
2个月前
已完结
G9a/GLP Modulators: Inhibitors to Degraders
3个月前
已完结
Targeting synapse function and loss for treatment of neurodegenerative diseases
7个月前
已完结
Synaptic degeneration in Alzheimer disease
7个月前
已完结
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