Lv6
2208 积分 2025-03-12 加入
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
9天前
已完结
Copper‐Catalyzed Tunable Oxygenative Rearrangement of Tetrahydrocarbazoles
26天前
已完结
C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity
1个月前
已完结
Novel ZnX2-ModulatedPd/C and Pt/C Catalysts for Chemoselective Hydrogenationand Hydrogenolysis of Halogen-Substituted Nitroarenes,Alkenes, Benzyl Ethers, and Aromatic Ketones
1个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
1个月前
已完结
Target identification and assessment in the era of AI
1个月前
已完结
Integrated Strategic Design and In Situ Click Chemistry Approach to Rapid Discovery of Novel Potent Covalent TEAD Inhibitors
1个月前
已关闭
Convenient synthesis of primary sulfonamides
2个月前
已完结
Construction of 3-Nitrocarbazoles via Domino Henry Reaction/Dehydration/Benzannulation of 2-Alkynylindole-3-carbaldehydes
3个月前
已完结
Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)
3个月前
已完结