Lv716
3670 积分 2025-01-26 加入
Discovery, Optimization, and Evaluation of Potent and Selective PDGFRβ Inhibitors for the Treatment of Hepatocellular Carcinoma
2天前
已完结
Discovery of pyrimidine-5-carboxamide derivatives as novel salt-inducible kinases (SIKs) inhibitors for inflammatory bowel disease (IBD) treatment
3天前
已完结
Structure–Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor
10天前
已完结
PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus
11天前
已完结
Mechanistic Insights into Chemoselective Reduction of Engineered Cysteine Residues in Antibodies Using Computational Modeling and Rationally Designed Phosphines
17天前
已完结
Identification of Novel Imidazo[1,2- b ]pyridazine Derivatives as Selective ROCK2 Inhibitors for the Treatment of Pulmonary Fibrosis
18天前
已完结
Rational Optimization of Rho-Associated Coiled-Coil Containing Protein Kinase 2 Inhibitors via Disruption of Molecular Planarity for Pulmonary Fibrosis
18天前
已完结
Drug Delivery Strategy Exploiting Amino Acid Prodrugs: Improving Oral Bioavailability and Overcoming Nonlinear Pharmacokinetic Challenges Following Dose Escalation of a CK2 Inhibitor with Poor Solubility
19天前
已完结
Liver-targeted delivery based on prodrug: passive and active approaches
24天前
已完结
Discovery of p300 histone acetyltransferase inhibitors bearing an imidazo[4,5-b]pyridine-2-one scaffold for the treatment of multiple myeloma
25天前
已完结
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