Lv7
4050 积分 2025-01-26 加入
TGFβ2 Regulates Human Trabecular Meshwork Cell Contractility via ERK and ROCK Pathways with Distinct Signaling Crosstalk Dependent on the Culture Substrate
30天前
已完结
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis
30天前
已完结
Impact of the SIK3 pathway inhibition on osteoclast differentiation via oxidative phosphorylation
1个月前
已完结
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+ Acute Myeloid Leukemia (AML)
1个月前
已完结
Discovery, Optimization, and Evaluation of Potent and Selective PDGFRβ Inhibitors for the Treatment of Hepatocellular Carcinoma
1个月前
已完结
Discovery of pyrimidine-5-carboxamide derivatives as novel salt-inducible kinases (SIKs) inhibitors for inflammatory bowel disease (IBD) treatment
1个月前
已完结
Structure–Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor
1个月前
已完结
PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus
1个月前
已完结
Mechanistic Insights into Chemoselective Reduction of Engineered Cysteine Residues in Antibodies Using Computational Modeling and Rationally Designed Phosphines
2个月前
已完结
Identification of Novel Imidazo[1,2- b ]pyridazine Derivatives as Selective ROCK2 Inhibitors for the Treatment of Pulmonary Fibrosis
2个月前
已完结