Lv5
1150 积分 2025-02-12 加入
Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody–drug conjugates
29天前
已完结
Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
30天前
已完结
Site‐Specific Multi‐Functionalization of the Carrier Protein CRM197 by Disulfide Rebridging for Conjugate Vaccine Development
1个月前
已关闭
Comparison of quaternary ammonium-based linkers for antibody-drug conjugates based on camptothecin derivatives
1个月前
已完结
A mechanistic and kinetic study of the E-ring hydrolysis and lactonization of a novel phosphoryloxymethyl prodrug of camptothecin
1个月前
已关闭
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate
3个月前
已完结
An Enzymatically Cleavable Tripeptide Linker for Maximizing the Therapeutic Index of Antibody–Drug Conjugates
3个月前
已完结
Site‐specific modification of native IgGs with flexible drug‐load
3个月前
已完结
Abstract LB124: Targeting NaPi2b with a novel dual TOP1i ADC that shows excellent biophysical properties and high efficacy in vivo
3个月前
已关闭
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