Lv6
3000 积分 2025-02-12 加入
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
1小时前
已完结
Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human
1天前
已完结
NQO1-responsive Trimethyl lock benzoquinone: A cleavable linker strategy for antibody-drug conjugates
5天前
已完结
Benzyl Ammonium Carbamates Undergo Two‐Step Linker Cleavage and Improve the Properties of Antibody Conjugates
15天前
已完结
Combination of chemotherapy and immune checkpoint therapy by the immunoconjugates-based nanocomplexes synergistically improves therapeutic efficacy in SCLC
27天前
已完结
A Multifunctional Peptide Linker Stably Anchors to Silica Spicules and Enables MMP-Responsive Release of Diverse Bioactive Cargos
27天前
已关闭
In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment
1个月前
已完结
Extracellular payload release from non-internalizing antibody–drug conjugates: mechanisms and linker technologies
1个月前
已完结
Electrochemical reduction of benzoic acid esters using water as a H/D source
1个月前
已完结
Biological Evaluation of Cleavable Linkers in Exatecan-Based Antibody–Drug Conjugates: A Comparative Study of DXd and Exo-Linker Platforms
1个月前
已完结
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