Lv61
2280 积分 2024-07-03 加入
Discovery of Novel and Highly Potent Wee1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia
3天前
已完结
DBeQ derivative targets VPS4 functions in cancer cells and suppresses tumor growth in mice
3天前
已完结
Wee1 Inhibitor Optimization through Deep-learning-driven Decision Making
9天前
已完结
Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760
24天前
已完结
Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders
24天前
已完结
Design, Synthesis, and Biological Evaluation of Indole Derivatives Targeting LsrK as AI-2 Quorum Sensing Inhibitors
24天前
已完结
ARE-PROTACs Enable Co-degradation of an Nrf2–MafG Heterodimer
1个月前
已完结
Discovery of Novel, Potent, Selective, and Orally Available DGKα Inhibitors for the Treatment of Tumors
1个月前
已完结
Discovery of a Novel MNK Inhibitor (NSP-1047) with In Vivo Anti-acute Myeloid Leukemia Activity
3个月前
已完结
Halogenation-Driven Discovery of Halomethylene-Biphenyl-Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Improved Safety and PK Profiles
3个月前
已完结
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