Lv7
3270 积分 2024-07-03 加入
USP22 in human cancers: mechanistic insights and inhibitor development
3天前
已完结
Design, synthesis, and biological evaluation of Wee1 kinase degraders
4天前
已完结
WEE1 inhibition in cancer therapy: Mechanisms, synergies, preclinical insights, and clinical trials
4天前
已完结
The effect of deuterated PLK1 inhibitor on its safety and efficacy in vivo
11天前
已完结
Toward a Small Molecule Therapy for Angelman Syndrome: Structure–Activity Relationship Studies of 3-Aminopyrazole Phenylacetamides as Paternal Ube3a Unsilencers
30天前
已完结
Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer
1个月前
已完结
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor
1个月前
已完结
Structure-Based Design of 4-(1-Methyl-1 H -indol-3-yl)pyrimidin-2-amine Derivatives as the First Covalent FGFR3 Selective Inhibitors
1个月前
已完结
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression
1个月前
已完结
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
1个月前
已完结
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