Lv63
2620 积分 2024-07-03 加入
Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839
2小时前
已完结
Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer
14天前
已完结
Identification of 3-aryl-5-methyl-isoxazole-4-carboxamide derivatives and analogs as novel HIF-2α agonists through docking-based virtual screening and structural modification
23天前
已完结
Discovery of a Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist and Its Synergistic Therapy with Prolyl Hydroxylase Inhibitors for the Treatment of Renal Anemia
23天前
已完结
SAR study of 1,2-benzisothiazole dioxide compounds that agonize HIF-2 stabilization and EPO production
23天前
已完结
Discovery of 3-(Arylamido)pyrazolopyridine HIF-2α Agonists and a Codrug Strategy with Prolyl Hydroxylase Inhibition for Synergistic Treatment of Renal Anemia
23天前
已完结
Lysine-Targeted Covalent Strategy Leading to the Discovery of Novel Potent PROTAC-Based PI3Kδ Degraders
1个月前
已完结
Modern perspectives on covalent and reversible covalent inhibitors: From selectivity to clinical translation
1个月前
已关闭
Covalent Inhibitors: To Infinity and Beyond
1个月前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
1个月前
已完结
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