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146 积分 2024-05-21 加入
Dual-targeting pharmacological UFMylation inhibition reprograms tumor and immune microenvironments to achieve long-term glioblastoma regression
24天前
已完结
Discovery of P11–2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer
1个月前
已完结
Targeting TROP2 in drug-tolerant persister cells delays EGFR tyrosine kinase inhibitor resistance in non-small-cell lung cancer
1个月前
已完结
EGFR N-Glycosylation Catalyzed by NDST2 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma
1个月前
已完结
Tumor-derived branched-chain α-keto acids activate Notch signaling in tumor-associated macrophages to limit immunity
1个月前
已完结
Tumor-derived branched-chain α-keto acids activate Notch signaling in tumor-associated macrophages to limit immunity
4个月前
已完结
CDK10 suppresses nucleic acid sensors-mediated antitumor immunity
5个月前
已完结
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin
5个月前
已完结
ETV5 transcriptionally activates LGR4 and promotes cancer cell invasion and migration of nasopharyngeal carcinoma
6个月前
已完结
Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
6个月前
已完结
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