Lv22
120 积分 2024-01-29 加入
Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the “Clamp” Strategy
7天前
已完结
Preclinical in vitro and in vivo activity of the RAF/MEK clamp avutometinib in combination with FAK inhibition in uterine carcinosarcomas
7天前
已完结
Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents
12天前
已完结
Binimetinib Is a Potent Reversible and Time-Dependent Inhibitor of Cytochrome P450 1A2
13天前
已关闭
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation
14天前
已完结
Tunlametinib: First Approval
14天前
已完结
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor
19天前
已完结
Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors
19天前
已完结
Targeting the SHOC2–RAS interaction in RAS-mutant cancers
20天前
已完结
A Review of Selumetinib in the Treatment of Neurofibromatosis Type 1–Related Plexiform Neurofibromas
25天前
已完结
皖公网安备34019202002308
