Lv4
570 积分 2025-06-26 加入
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors
23天前
已完结
Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia
1个月前
已完结
Recruitment of FBXO22 for Targeted Degradation of NSD2
2个月前
已完结
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
4个月前
已完结
Hydrophobic tagging of small molecules: an overview of the literature and future outlook
6个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
7个月前
已完结
Synthesis of spiropyrazoline oxindoles by a formal [4 + 1] annulation reaction between 3-bromooxindoles and in situ-derived 1,2-diaza-1,3-dienes
7个月前
已完结
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia
8个月前
已完结
The CDK4/6 inhibitor revolution — a game-changing era for breast cancer treatment
9个月前
已完结
A review of HCV protease inhibitors
10个月前
已关闭