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From Undruggable to Degradable: Strategic Expansion of Targeted Protein Degradation in Cancer Therapy
9天前
已完结
Extracellular targeted protein degradation: an emerging modality for drug discovery
9天前
已完结
Lysosome-targeting chimaeras for degradation of extracellular proteins
9天前
已完结
The coming of age of chaperone-mediated autophagy
9天前
已完结
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders
9天前
已完结
Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
9天前
已完结
Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway
9天前
已完结
Discovery and resistance mechanism of a selective CDK12 degrader
9天前
已完结
Research Advances in Chaperone-Mediated Autophagy (CMA) and CMA-Based Protein Degraders
9天前
已完结
Extracellular targeted protein degradation: an emerging modality for drug discovery
15天前
已完结
Reactive organic matter destabilizes Fe-mediated phosphorus retention through Fe-S-P decoupling in lake sediments
12天前
已采纳
GenCeption: Evaluate vision LLMs with unlabeled unimodal data
28天前
已采纳
GenCeption: Evaluate vision LLMs with unlabeled unimodal data
28天前
已采纳
Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort
28天前
已采纳
Hierarchically engineered PAMA@ZnFeCo-PBA hybrid flame-retardant for polypropylene with enhanced fire safety and preserved mechanical and dielectric properties
28天前
已采纳
Nanosecond Pulsed Electric Fields (nsPEFs) Modulate Electron Transport in the Plasma Membrane and the Mitochondria
28天前
已采纳
Conversion of tropical rainforest to rubber plantations reshapes soil organic carbon sequestration through divergent accrual of plant lignin and microbial residues
28天前
已采纳
Conversion of tropical rainforest to rubber plantations reshapes soil organic carbon sequestration through divergent accrual of plant lignin and microbial residues
28天前
已采纳
Research of carrying mechanism between β-lactoglobulin and linoleic acid: Effects on protein structure and oxidative stability of linoleic acid
28天前
已采纳
Corrigendum to ‘Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection’ [Eur J Med Chem. 263 (2024) 115972]
28天前
已采纳