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1020 积分 2025-07-16 加入
Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy
3天前
已完结
Construction of Small‐Molecule Deubiquitinase‐Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo
3天前
已完结
Large‐Scale Profiling of Kinase Degradation by Using Norbornene‐Based Hydrophobic Tag (HyT) Strategy
4天前
已完结
Sulfatase-Induced In Situ Formulation of Antineoplastic Supra-PROTACs
4天前
已完结
Proteasome Cap Targeting Chimeras for Ubiquitination‐Independent Targeted Protein Degradation
5天前
已完结
Proteasome Cap Targeting Chimeras for Ubiquitination‐Independent Targeted Protein Degradation
5天前
已完结
Multiplexed Photo-Cross-Linking Reveals Comprehensive Midnolin Interactome: Insights into Ubiquitin-Independent Degradation and Functional Diversity
5天前
已完结
Reactive Oxygen Species-Instructed Supramolecular Assemblies Enable Bioorthogonally Activatable Protein Degradation for Pancreatic Cancer
5天前
已完结
Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo
5天前
已完结
Rational Proteolysis Targeting Chimera Design Driven by Molecular Modeling and Machine Learning
5天前
已完结
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