Lv11
48 积分 2025-08-13 加入
A structure–activity relationship study of the positive allosteric modulator LY2033298 at the M 4 muscarinic acetylcholine receptor
8小时前
待确认
Synthesis and Structure–Activity Relationships of Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor
27天前
已完结
Structure-activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine D₂ receptor
1个月前
已完结
Discovery of novel selective HDAC6 inhibitors via a scaffold hopping approach for the treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo
1个月前
已完结
Discovery of novel tryptamine derivatives as GluN2B subunit-containing NMDA receptor antagonists via pharmacophore-merging strategy with orally available therapeutic effect of cerebral ischemia
1个月前
已完结
Asymmetric Reductive Cross-Coupling of Aldimines
1个月前
已完结
Discovery and Evaluation of N -Arylindole-Based GluN2B-NMDAR Antagonists with Reduced Cardiotoxicity for the Treatment of Ischemic Stroke
1个月前
已完结
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
3个月前
已完结
New chromophores based on 2-(4-vinylchromen-2-ylidene)malononitrile and 2-(2-vinylchromen-4-ylidene)malononitrile
1年前
已完结
Copper Promoted Coupling Reaction I. Phenylation of O-H and N-H Compounds with C6H5X by Using Copper Catalyst Itself as the Acceptor of HX Released
1年前
已完结
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