Lv11
80 积分 2022-10-17 加入
Crisugabalin, a ligand for the αδ subunit of voltage-gated calcium channels, exhibits no obvious abuse potential in rodents
5小时前
已关闭
Discovery, Structure–Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain
6小时前
已完结
Discovery of (S)-1-((2′,6-Bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain
6小时前
已完结
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain
6小时前
已完结
Angiotensin II Type 2‐Receptor: New Clinically Validated Target in the Treatment of Neuropathic Pain
17天前
已完结
Selective small molecule angiotensin II type 2 receptor antagonists for neuropathic pain
17天前
已完结
Efficacy and safety of EMA401 in peripheral neuropathic pain: results of 2 randomised, double-blind, phase 2 studies in patients with postherpetic neuralgia and painful diabetic neuropathy
17天前
已完结
Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study
17天前
已完结
Asthma Management in Adults
17天前
已完结
Type 2 severe asthma: pathophysiology and treatment with biologics
17天前
已完结
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