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18 积分 2023-01-30 加入
Inavolisib-Based Therapy in PIK3CA -Mutated Advanced Breast Cancer
12小时前
已完结
Abstract PO3-25-09: OKI-219, a PI3KαH1047R-mutant-selective inhibitor demonstrates efficacy as a single agent and drives combination responses with standard of care therapies in pre-clinical PI3KαH1047R mutant breast cancer models
15小时前
已完结
Abstract LB437: LAE118, a pan mutant-selective PI3Ka inhibitor with superb activity against both the kinase domain and helical domain mutants
1个月前
已关闭
Abstract P3-08-19: Preliminary results from PIKture-01, a First-in-Human Study of OKI-219, a mutant selective inhibitor of PI3Kα-H1047R, in mutant selected solid tumors including breast cancer
1个月前
已完结
In silico discovery of a novel potential allosteric PI3Kα inhibitor incorporating 2-oxopropyl urea targeting head and neck squamous cell carcinoma
2个月前
已完结
Structural Insights into the Development of Inhibitors Against Cancer-Specific Mutations of PI3Kα
2个月前
已完结
Preclinical evaluation and phase 1 study of the PI3Kα/δ inhibitor TQ‐B3525 in Chinese patients with advanced cancers
3个月前
已完结
Reductive synthesis of azoxypyridines from nitropyridines using hydroxides in alcoholic media
7个月前
已完结
Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases
7个月前
已完结
Nanosponge hierarchical micro-mesoporous MFI zeolites as a high-performance catalyst for the hydroamination of methyl acrylate with aniline
11个月前
已完结
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