Lv1
30 积分 2025-05-16 加入
Discovery of Bisindoles that Activate Tumor-Associated Macrophages and Enhance Antitumor Immunity
9个月前
已完结
Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy
9个月前
已完结
Covalent Recruitment of NEDD4 for Targeted Protein Degradation: Rational Design of Small Molecular Degraders
9个月前
已完结
Design, synthesis, and biological evaluation of KDM5B degraders against hematologic malignancy cells
9个月前
已完结
KRASG12D Selective VHL-PROTAC with sparing KRASWT and Other KRAS Mutants
9个月前
已完结
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia
10个月前
已完结
KRASG12D Selective VHL-PROTAC with sparing KRASWT and Other KRAS Mutants
10个月前
已完结
Synthesis and apoptotic induction of sulfonamide-based chalcone hybrids as first-in-class dual histone deacetylase‑carbonic anhydrase inhibitors with potential anti-tubulin activity
10个月前
已关闭
Synthesis of quinazoline derivatives and their in vitro inhibition activity against MDA-MB-231 cells and A549 cells
10个月前
已关闭
Rational Design and Multi‐tiered Computational Evaluation of Novel Darunavir Derivatives as HIV‐1 Protease Inhibitors: an Integrated Approach Using QSAR Model, Molecular Docking, MD Simulations, DFT Analysis, and ADME Profiling
10个月前
已完结
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