Lv1
40 积分 2025-05-16 加入
Discovery of the ERα-Targeting PROTACs with Intrinsic Fluorescence for Precision Theranostics of Breast Cancer
4天前
已完结
Rational design and discovery of potent PROTAC degraders of ASK1: A targeted therapy in MASH
5天前
已完结
Design, synthesis and antiproliferative effects evaluation of ferritin-targeted degraders
5天前
已完结
Structure-guided Design of a Methyltransferase-like 3 (METTL3) Proteolysis Targeting Chimera (PROTAC) Incorporating an Indole-Nicotinamide Chemotype
5天前
已完结
Discovery of nonpungent Transient Receptor Potential Vanilloid (TRPV1) agonist antedrugs for treatment of dysphagia
7天前
已关闭
Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules
10天前
已完结
Double Swords in One: Novel Selective PI3K/110β PROTAC Degraders for the Treatment of Multidrug-Resistant Cancer by Activating ERS and Inhibiting P-gp
10天前
已完结
Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy
10天前
已完结
MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration
10天前
已完结
Discovery of APH02174 as a Highly Selective and Orally Bioavailable IRAK4 Degrader for the Treatment of Inflammatory Diseases
12天前
已完结
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