Lv2
128 积分 2023-07-04 加入
Elucidating conformational dynamics of GDP/GTP-KRAS complexes caused by mutations from the switch domain I through Gaussian accelerated molecular dynamics simulations
16小时前
已完结
Therapeutic exploration of biased ligands at class A G protein-coupled receptors over the past 20 years
2个月前
已完结
Attributes novel drug candidate: Constitutive GPCR signal bias mediated by purinergic receptors
2个月前
已完结
Molecular glues as GPCR modulators: unveiling three distinct mechanistic pathways for signal regulation
3个月前
已完结
Biased Agonists of the Type 1 Angiotensin II Receptor Promote Distinct Subcellular β-Arrestin Conformations
3个月前
已完结
Machine Learning Navigated Allosteric Network to Unveil Biased Allosteric Modulation of GPCRs
3个月前
已完结
Virtual Compound Screening for Discovery of Dopamine D1 Receptor Biased Allosteric Modulators
3个月前
已完结
Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3
5个月前
已完结
Molecular glues as potential GPCR therapeutics
5个月前
已完结