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24 积分 2024-09-09 加入
Biophysical and Computational Approaches to Study Ternary Complexes: A ‘Cooperative Relationship’ to Rationalize Targeted Protein Degradation
27天前
已完结
Shotgun Approach for PROTAC Ternary Complex Modeling and Evaluation
27天前
已完结
Construction of Small‐Molecule Deubiquitinase‐Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo
1个月前
已完结
Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugs
1个月前
已完结
Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway
1个月前
已完结
A chemical probe to modulate human GID4 Pro/N-degron interactions
1个月前
已完结
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
1个月前
已完结
Molecular glue CELMoD compounds are regulators of cereblon conformation
1个月前
已完结
Identification of an allosteric site on the E3 ligase adapter cereblon
1个月前
已完结
Crbn-based molecular Glues: Breakthroughs and perspectives
1个月前
已完结
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