Lv11
18 积分 2023-12-09 加入
Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement
1小时前
待确认
Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders
3小时前
已完结
Design, Synthesis, and Bioevaluation of Novel NLRP3 Inhibitor with IBD Immunotherapy from the Virtual Screen
3小时前
已完结
Phase 2 Trial of Icotrokinra for Patients with Ulcerative Colitis
1天前
已完结
Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis
14天前
已完结
ABBV-319: a CD19-targeting glucocorticoid receptor modulator antibody-drug conjugate therapy for B-cell malignancies
15天前
已完结
Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
15天前
已完结
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate
16天前
已完结
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody–Drug Conjugates
19天前
已完结
Development of Anti-CD74 Antibody–Drug Conjugates to Target Glucocorticoids to Immune Cells
20天前
已完结