Lv4
458 积分 2023-12-22 加入
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia
1个月前
已完结
Rational design of next-generation PDK1 modulators: Addressing selectivity and resistance through molecular insights — A medicinal chemistry perspective
1个月前
已完结
Radical Borylation of Alkyl Bromides by Photoinduced Halogen‐Atom Transfer
3个月前
已完结
1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), α1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics
3个月前
已完结
Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)
3个月前
已完结
Energy transfer-enabled unsymmetrical diamination using bifunctional nitrogen-radical precursors
3个月前
已完结
Triphenylphosphonium-based mitochondrial targeting in cancer therapy: mechanisms, progress, and perspectives
3个月前
已完结
Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
3个月前
已完结
Modular Synthesis of Desferrioxamine B and Its Methotrexate Conjugate as a Selective Trojan Horse Antibiotic That Targets Streptococcus pneumoniae
3个月前
已完结
Azolylpyrimidinediols as Novel Structural Scaffolds of DNA-Groove Binders against Intractable Acinetobacter baumannii
3个月前
已完结
皖公网安备34019202002308
