Zzzhuan
Lv1
20 积分
2023-10-08 加入
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Randomized Placebo-Controlled Study of the Safety, Tolerability, Antiviral Activity, and Pharmacokinetics of 10-Day Monotherapy With BMS-986001, a Novel HIV NRTI, in Treatment-Experienced HIV-1–Infected Subjects
1天前
已完结
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Randomized, placebo‐controlled single‐ascending‐dose study to evaluate the safety, tolerability and pharmacokinetics of the HIV nucleoside reverse transcriptase inhibitor, BMS‐986001, in healthy subjects
1天前
已完结
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Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury
4天前
已完结
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Enhancing standard of care chemotherapy efficacy using DNA-dependent protein kinase (DNA-PK) inhibition in preclinical models of Ewing sarcoma
9天前
已完结
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Recent Progress in DNA Damage Response-Targeting PROTAC Degraders
16天前
已完结
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DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
1个月前
已完结
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Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers
1个月前
已完结
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Discovery of Novel Heterotricyclic Compounds as DNA-Dependent Protein Kinase (DNA-PK) Inhibitors with Enhanced Chemosensitivity, Oral Bioavailability, and the Ability to Potentiate Cancer Immunotherapy
1个月前
已完结
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Cellular senescence in ageing: from mechanisms to therapeutic opportunities
1个月前
已完结
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Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
1个月前
已完结