Lv01
0 积分 2025-09-12 加入
Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor
6小时前
待确认
Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
7小时前
已完结
Discovery of highly potent dual GSPT1/BRD4 degraders with anti-AML activity
13天前
已完结
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
1个月前
已完结
Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells
3个月前
已完结
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C
3个月前
已完结
Discovery of 2-(1-(3-Chloro-4-cyanophenyl)-1H-pyrazol-3-yl)acetamides as Potent, Selective, and Orally Available Antagonists Targeting the Androgen Receptor
3个月前
已完结
Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics
3个月前
已完结
Identification of Oral Bioavailable Coumarin Derivatives as Potential AR Antagonists Targeting Prostate Cancer
3个月前
已完结
UHRF1 regulates AR ubiquitination to promote the loss of AR signaling and enzalutamide resistance in progression of prostate cancer
3个月前
已完结