Lv3
280 积分 2025-12-25 加入
Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
1个月前
已完结
Highly selective HPK1 inhibitor NDI-101150 mediates immune cell activation and robust antitumor responses, distinct from immune checkpoint blockade
1个月前
已关闭
P01.08 Discovery of CRD1601, a potent and selective HPK1 inhibitor with robust in vivo anti-cancer activity
1个月前
已关闭
444 (PB432): First-in-human phase 1 study of RGT-264, a potent hematopoietic progenitor kinase 1 (HPK1) inhibitor in patients (pts) with advanced solid tumors
1个月前
已完结
465 (PB453): RGT-264 a highly potent, selective and orally bioavailable HPK1 (MAP4K1) inhibitor augments immune activation and anti-tumor immunity
1个月前
已关闭
Discovery of a Novel Potent and Orally Efficacious PROTAC Degrader of HPK1 for Tumor Immunotherapy
2个月前
已完结
Discovery of an Exceptionally Orally Bioavailable and Potent HPK1 PROTAC with Enhancement of Antitumor Efficacy of Anti-PD-L1 Therapy
2个月前
已完结
An Oral PROTAC Targeting HPK1 Degradation Potentiates Anti‐Solid Tumor Immunity
2个月前
已完结
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy
2个月前
已完结
Projecting cancer incidence and mortality using Bayesian ageperiodcohort models
1个月前
已采纳
Liquid platelet-rich fibrin produced via horizontal centrifugation decreases the inflammatory response and promotes chondrocyte regeneration in vitro
1个月前
已采纳
Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging
1个月前
已采纳
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