Lv3
252 积分 2025-12-31 加入
Exploration of tricyclic heterocycles as core structures for RIOK2 inhibitors
1小时前
待确认
Exploration of inhibitors targeting KIF18A with ploidy-specific lethality
3天前
已完结
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe
3天前
已完结
Optimization and structure–activity relationship of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides: Identification of MK-0873, a potent and effective PDE4 inhibitor
14天前
已完结
Discovery of 4-[(Z)-(4-Bromophenyl)- (ethoxyimino)methyl]-1‘-[(2,4-dimethyl-3- pyridinyl)carbonyl]-4‘-methyl-1,4‘- bipiperidine N-Oxide (SCH 351125): An Orally Bioavailable Human CCR5 Antagonist for the Treatment of HIV Infection
14天前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
1个月前
已完结
The evolving landscape of RAS-targeted therapies
1个月前
已完结
The Metabolic Landscape of RAS-Driven Cancers from biology to therapy
1个月前
已完结
Silencing of Oncogenic KRAS by Mutant-Selective Small Interfering RNA
1个月前
已完结
A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment
1个月前
已完结
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