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40 积分 2024-03-16 加入
Abstract CT116: BMS-986205, an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic (PD) activity, alone and in combination with nivolumab (nivo) in advanced cancers in a phase 1/2a trial
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Neurobiological mechanisms in the kynurenine pathway and major depressive disorder
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Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists
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Engineered hybrid membrane vesicles combined with autologous and synthetic antigens as therapeutic vaccines to efficiently suppress tumor recurrence
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Design, Synthesis, and Biological Evaluation of Novel Hydroxyamidine Derivatives as Indoleamine 2,3-Dioxygenase 1 Inhibitors
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Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies
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