Lv6
1750 积分 2024-01-14 加入
Stick it to E3s
1天前
待确认
Pan-KRAS destruction with a single PROTAC
1天前
待确认
Computational Fragment-Based Design Facilitates Discovery of Potent and Selective Monoamine Oxidase-B (MAO-B) Inhibitor
18天前
已完结
A patent review of PRMT5 inhibitors to treat cancer (2018 - present)
22天前
已完结
Medicinal chemistry insights into PRMT5 inhibitors
1个月前
已完结
Discovery of Covalently-bound, First-in-Class Allosteric Inhibitor of PRMT5
1个月前
已关闭
Design, synthesis and evaluation of 1,2-dihydropyrido[2,3-d]pyrimidine-6‑carbonitrile derivatives as novel covalent inhibitors for the treatment of KRASG12C-mutant NSCLC
1个月前
已完结
Efficient targeted oncogenic KRASG12C degradation via first reversible-covalent PROTAC
2个月前
已完结
Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer
3个月前
已完结
Identification of novel Pyrrolo[2,3-d]Pyrimidine-based KRAS G12C inhibitors with anticancer effects
4个月前
已完结