Lv3
344 积分 2024-02-12 加入
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK
16天前
已完结
Overcoming the Hydrolytic Susceptibility of Thiol-Reactive Reversible Warheads through the Development of Substituted Phenyl Cyanoacrylamides
16天前
已完结
Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be “Switched Off” via Bioorthogonal Chemistry Inside Live Cells
16天前
已完结
Proteome-Wide Covalent Targeting of Acidic Residues with Tunable N-Aryl Aziridines
16天前
已完结
Cell Membrane-Anchored Click Reaction Enhances Porphyrin Uptake for Highly Efficient Photodynamic Therapy of Breast Tumors
22天前
已完结
Computational insights into the interaction of small molecule inhibitors with HRI kinase domain
1个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
1个月前
已完结
Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway
1个月前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
2个月前
已完结
Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma
2个月前
已完结
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