Lv31
342 积分 2024-02-12 加入
Inhalable Polymeric PROTAC Nanococktail for Targeted Protein Degradation in Idiopathic Pulmonary Fibrosis
5小时前
待确认
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK
4个月前
已完结
Overcoming the Hydrolytic Susceptibility of Thiol-Reactive Reversible Warheads through the Development of Substituted Phenyl Cyanoacrylamides
4个月前
已完结
Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be “Switched Off” via Bioorthogonal Chemistry Inside Live Cells
4个月前
已完结
Proteome-Wide Covalent Targeting of Acidic Residues with Tunable N-Aryl Aziridines
4个月前
已完结
Cell Membrane-Anchored Click Reaction Enhances Porphyrin Uptake for Highly Efficient Photodynamic Therapy of Breast Tumors
4个月前
已完结
Computational insights into the interaction of small molecule inhibitors with HRI kinase domain
4个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
4个月前
已完结
Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway
5个月前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
5个月前
已完结
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