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390 积分
2022-04-29 加入
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Copper‐catalyzed intramolecular annulation through C–H activation: Synthesis of carbazolones
5天前
已完结
Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis
21天前
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Directing group assisted rhodium catalyzed meta-C–H alkynylation of arenes
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CDK inhibitors from past to present: A new wave of cancer therapy
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Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical Development
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Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
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Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs
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The Effect of Breast Cancer Resistance Protein and P-Glycoprotein on the Brain Penetration of Flavopiridol, Imatinib Mesylate (Gleevec), Prazosin, and 2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic Acid (PF-407288) in Mice
4个月前
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Application of a high‐resolution in vitro human MDR1‐MDCK assay and in vivo studies in preclinical species to improve prediction of CNS drug penetration
4个月前
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