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30 积分 2024-10-15 加入
Mixed-Lineage Kinase 1 and Mixed-Lineage Kinase 3 Subtype-Selective Dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: Optimization, Mixed-Lineage Kinase 1 Crystallography, and Oral in Vivo Activity in 1-Methyl-4-phenyltetrahydropyridine Models
16天前
已完结
Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis
17天前
已完结
Polypharmacological Drug Design Guided by Integrating Phenotypic and Restricted Fragment Docking Strategies
17天前
已完结
Structural Basis of Sequential Enantioselective Epoxidation by a Flavin‐Dependent Monooxygenase in Lasalocid A Biosynthesis
27天前
已完结
Selective activation of TWIK-related acid-sensitive K + 3 subunit–containing channels is analgesic in rodent models
2个月前
已完结
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