Lv3
316 积分 2024-10-12 加入
Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and StructureActivity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
9小时前
待确认
Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently
9小时前
已完结
Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
9小时前
已完结
Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
9小时前
已完结
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
10小时前
已完结
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
10小时前
已完结
Phthalimide conjugation as a strategy for in vivo target protein degradation
10小时前
已完结
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
10小时前
已完结
Targeted protein degradation: expanding the toolbox
10小时前
已完结
Identification of a Primary Target of Thalidomide Teratogenicity
10小时前
已完结
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