Lv2
160 积分 2025-04-17 加入
Compatibility of Caco-2 cells with Simulated Intestinal Fluid-Predicting Permeability
17天前
已关闭
Cytochrome P450 3A Time-Dependent Inhibition Assays Are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants
1个月前
已完结
Improvement in static and dynamic projections of drug-drug interactions caused by cytochrome P4503A time-dependent inhibitors through in vitro allosteric modulation by progesterone
1个月前
已关闭
Quantitative Systems Toxicology Identifies Independent Mechanisms for Hepatotoxicity and Bilirubin Elevations Due to AKR1C3 Inhibitor BAY1128688
5个月前
已完结
Assessing Liver Effects of Cannabidiol and Valproate Alone and in Combination Using Quantitative Systems Toxicology
5个月前
已完结
Improved clearance predictions for aldehyde oxidase substrates using a novel triculture human hepatocyte model
5个月前
已关闭
A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept
5个月前
已完结
Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism
5个月前
已关闭
Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism
7个月前
已关闭
Influence of Drugs Interacting with CYP3A4 on the Pharmacokinetics, Pharmacodynamics, and Safety of the Prandial Glucose Regulator Repaglinide
7个月前
已完结
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