Lv5
951 积分 2021-01-09 加入
Heterobifunctional proteomimetic polymers for targeted degradation of MYC and KRAS
13天前
已完结
Targeted degradation of c-Myc through the midnolin–proteasome pathway
13天前
已完结
Discovery of 4-(4-(3-(1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazole-2-yl)isoxazol-5-yl)phenyl)morpholine as a novel c-Myc inhibitor against lung cancer in vitro and in vivo
13天前
已完结
AML-147 C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill In Vitro and In Vivo in Acute Myeloid Leukemia and Lymphomas
13天前
已完结
MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation
13天前
已完结
Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC
17天前
已完结
A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors
17天前
已完结
Rational discovery of molecular glue degraders via scalable chemical profiling
17天前
已完结
In situ spatiotemporal tracking of endogenous protein dynamics with allosteric genetically encoded biosensor in living cells
17天前
已完结
Identification of ACSL4 as a biomarker and contributor of ferroptosis
26天前
已完结