Lv11
68 积分 2022-10-27 加入
Expanding the binding space of argonaute-2: incorporation of either E or Z isomers of 6′-vinylphosphonate at the 5′ end of the antisense strand improves RNAi activity
3小时前
待确认
Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance
8天前
已关闭
Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model
22天前
已关闭
Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors
22天前
已完结
Virtual screening, molecular simulations and bioassays: Discovering novel microsomal prostaglandin E Synthase-1 (mPGES-1) inhibitors
27天前
已完结
Structural insights into RNA cleavage by PIWI Argonaute
30天前
已完结
Exploring the potential of structural modeling and molecular docking for efficient siRNA screening: A promising approach to Combat viral mutants, with a focus on HIV-1
1个月前
已完结
Optimizing siRNA Therapeutics Targeting HIF-1α: Computational Design, Screening, and Molecular Dynamics Simulation Studies
1个月前
已完结
Molecular dynamics simulation of siRNA loading into a nanoemulsion as a potential carrier
1个月前
已完结
Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review
1个月前
已完结
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