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4540 积分 2023-01-09 加入
Abstract 4539: ZM-2311 a novel and highly potent Polθ inhibitor demonstrates synergistically anti-tumor activities in combination with different therapeutics
19天前
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The synthesis and evaluation of a series of novel fused rings based benzothiazole derivatives as potent Polθ inhibitors
20天前
已完结
NAD+ precursor supplementation in human ageing: clinical evidence and challenges
29天前
已完结
Chemoproteomics-guided development of SLC15A4 inhibitors with anti-inflammatory activity
2个月前
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Discovery of a novel series of selective macrocyclic PKCTheta inhibitors
6个月前
已完结
Exploring New Potential Pkcθ Inhibitors Using Pharmacophore Modeling, Molecular Docking Analysis, and Molecular Dynamics Simulations
7个月前
已完结
Efficacy of a novel oral, potent, and highly selective PKCt inhibitor in the SCID T-cell transfer colitis model
7个月前
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Selective small-molecule PKC-theta inhibitors effectively block TCR-mediated activation of naïve peripheral blood and tissue resident memory T cells
7个月前
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HPG1860 in patients with NASH: a phase II double-blind, placebo-controlled, dose-ranging study
8个月前
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Moxibustion improves experimental colitis in rats with Crohn’s disease by regulating bile acid enterohepatic circulation and intestinal farnesoid X receptor
8个月前
已完结
Multiple effects contributed to the intensive shaking recorded in the 6 February 2023 Kahramanmaraş (Türkiye) earthquake sequence
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