Lv1
40 积分 2022-07-15 加入
Preclinical evaluation of zirconium-89 labeled anti-Trop2 antibody–drug conjugate (Trodelvy) for imaging in gastric cancer and triple-negative breast cancer
10小时前
已完结
Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development
29天前
已完结
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion
29天前
已完结
Rb1 deficiency induces synthetic lethality with ATR and PKMYT1 coinhibition in breast cancer cell lines and
1个月前
已完结
Large-scale simultaneous measurement of epitopes and transcriptomes in single cells
1个月前
已完结
Site-Selective Anti-PD-L1 Antibody–MMAE Conjugate for Enhanced NSCLC Therapy
1个月前
已完结
Site-Selective Antibody–Drug Conjugation by a Proximity-Driven S to N Acyl Transfer Reaction on a Therapeutic Antibody
1个月前
已完结
Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models
1个月前
已完结
Feedback activation of MAPK-ERK1/2 signaling causes resistance to trastuzumab-deruxtecan in endometrial cancers
1个月前
已关闭
Exploiting synthetic lethality in PDAC with antibody drug conjugates and ATR inhibition
1个月前
已完结